NutriLock™ and TauroLock™ solutions

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NutriLock™ TauroLock™ Documents

NutriLock™

NutriLock™ has been approved for instillation in all central-venous access systems. NutriLock™ prevents the formation of bacterial biofilm and thereby keeps catheters infection-free. NutriLock™ containt one active ingredient, taurolidine. This substance has a broad antimicrobial activity against gram-positive and gram-negative bacteria (incl. MRSA and VRE) and fungi (e.g. Candida). NutriLock™ is a citrat-free lock solution and doesn’t contain any anticoagulant. NutriLock™ is recommended for catheters in parenteral nutrition where the catheter isn’t exposed to blood or as an alternative to those patients where citrate for any reason should be avoided. In-between food intakes via parenteral nutrition or chemotherapy sessions, NutriLock™ remains in the vascular access. Please note that medical staff must respect the filling volume of each catheter or port system. Before using NutriLock™, please read the ”Instruction for use”.

NutriLock™

Available in:

3ml ampoules, 10 ampoules per package (TP-07-3)

TauroLock™ solutions

TauroLock™ solutions are catheter lock solutions with antimicrobial and anticoagulant efficacy. TauroLock™ solutions have been approved for instillation in all central-venous catheters (CVC). TauroLock™ solutions prevent the formation of biofilm and patients remain protected against catheter-related infections and occlusions.

TauroLock™ solutions:

Are bactericidal and fungicidal lock solutions, within 2-4 hours 500 microorganisms are killed
Prevents the formation of biofilm in the catheter
Maintains catheter patency
Are safe for patients and staff
Can be used for both children and adults

On the manufacturer’s website www.taurolock.com there is a possibility to register and get access to many of the studies that are made with TauroLock™ solutions.

The following types of TauroLock™ solutions are available:

TauroLock™

TauroLock™ is a catheter lock solution with antimicrobial and anticoagulant efficacy. The two active ingredients of TauroLock™ are taurolidine and 4 % citrate. Taurolidine has a broad antimicrobial activity (incl. MRSA and VRE) against gram-positive and gram-negative bacteria and fungi (e.g. Candida). Citrate works as an anticoagulant and helps to maintain an adequate flow rate within the catheter. In-between treatment sessions, TauroLock™ is instilled into the vascular access system. Please note that medical staff must respect the filling volume of each catheter or port system. TauroLock™ is recommended for all vascular access devices (VADs) in parenteral nutrition, oncology, and – as an alternative to TauroLock™-HEP500 or TauroLock™-U25.000 in hemodialysis. TauroLock™ has to be aspirated before using the VAD. Before using TauroLock™, please read the ”Instruction for use”.

Available in:

3 mL in ampoule, 10 ampoules per pack (TP-01-3)

5 mL in ampoule, 10 ampoules per pack (TP-01-5)

10 mL in vial , 100 vials per pack (TP-01-10)

TauroLock™-HEP100

TauroLock™-HEP100 is recommended for catheters that requires a stronger prophylaxis against occlusion than TauroLock™. TauroLock™-Hep100 contains three active ingredients: taurolidine, citrate (4 %) and heparin (100 units per ml). Taurolidine has a broad antimicrobial activity (incl. MRSA and VRE) against gram-positive and gram-negative bacteria and fungi (e.g. Candida). Heparin and citrate both help to prevent occlusions within the catheter. TauroLock™-HEP100 is instilled in-between treatment sessions and is recommended for all vascular access devices (VADs) in oncology and parenteral nutrition. Please note that medical staff must respect the filling volume of each catheter or port system. TauroLock™-HEP100 has to be aspirated before using the VAD. Before using TauroLock™-HEP100, please read the ”Instruction for use”.

Available in:

3 mL in ampoule, 10 ampoules per pack (TP-03-3)

TauroLock™-HEP500

TauroLock™-HEP500 prevents the formation of bacterial biofilm, patients remain protected against catheter-related infections and maintain a high patency rate. TauroLock™-Hep500 consists of three active ingredients: taurolidine, heparin (500 units per ml) and citrate (4 %). Taurolidine has a broad antimicrobial activity (incl. MRSA and VRE) against gram-positive and gram-negative bacteria and fungi (e.g. Candida). Heparin and citrate both prevent occlusions within the catheter. TauroLock™-HEP500 is instilled into the vascular access device (VAD) in-between treatment sessions and is recommended for hemodialysis-catheters. Please note that medical staff must respect the filling volume of each catheter or port system. TauroLock™-HEP500 has to be aspirated before using the VAD. Before using TauroLock™-HEP500, please read the ”Instruction for use”.

Available in:

5 mL in ampoule, 10 ampoules per pack (TP-02-5)

10 mL in vial, 100 vials per pack (TP-02-10)

TauroLock™-U25.000

TauroLock™-U25.000 prevents the formation of bacterial biofilms within catheters: Patients can avoid infections and maintain a high patency rate. TauroLock™-U25.000 is based on three active ingredients: taurolidine, citrate (4 %) and urokinase (25,000 units). Taurolidine has a broad antimicrobial activity (incl. MRSA and VRE) against gram-positive and gram-negative bacteria and fungi (e.g. Candida). Citrate works as an anticoagulant and urokinase has a thrombolytic effect, breaking up blood clotting in its early stages. TauroLock™-U25.000 is instilled in-between treatment sessions and is recommended as an addition to TauroLock™-HEP500 in vascular access devices (VADs) in hemodialysis or for other VADs requiring thrombolytic prophylaxis. Please note that medical staff must respect the filling volume of each catheter or port system. TauroLock™-U25.000 has to be aspirated before using the VAD. Before using TauroLock™-U25.000, please read the ”Instruction for use”.

Available in:

5 mL in ampoule + urokinase 25000 E in a vial, 5 ampoules and 5 vials per pack (TP-05)

Documentation

Brochures

TauroLock™ Portfolio TauroLock™ Triple Efficacy TauroLock™ 2+1

Instruction For Use

TauroLock™ Instruction For Use TauroLock™-HEP100 Instruction For Use TauroLock™-HEP500 Instruction For Use TauroLock™-U25.000 Instruction For Use NutriLock™ Instruction For Use

Other

FAQ TauroLock™ safety data sheet Table Catheter Lock-solutions dialysis Table Catheter Lock-solutions oncology and parenteral nutrition TauroLock™ instillation protocol TauroLock™-HEP100 instillation protocol TauroLock™-HEP500 instillation protocol TauroLock™-U25.000 instillation protocol NutriLock™ instillation protocol

Transcutan is marketing and selling NutriLock™ and TauroLock™ in Sweden.

For more information regarding dialysis catheters: kristina.ekberg@transcutan.com
For more information regarding other catheters: tindra.wikstrom@transcutan.com

For other countries contact the manufacturer TauroPharm.

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